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Swept lasers have facilitated paradigm shifts in biomedical imaging and diagnostics. The SWEEPICS project aims to research and develop the next generation of swept source lasers with flexible pulse modulation capability, high power output, multi-wavelength coherent output, and multi-application potential.

SWEEPICS will pioneer new laser-based systems, including a high-speed, high-resolution multiphoton high-content screening system, a multimodal non-invasive imaging system based on high-speed photoacoustics and multiphoton microscopy, and a smart microscope for accelerated acquisition and diagnostics. The interdisciplinary consortium of European partners will demonstrate the SWEEPICS technology in cutting-edge use cases, utilising novel vascular organoids for animal-free drug testing and infection studies.

This disruptive SWEEPICS technology will rapidly generate high-resolution diagnostic imaging in three dimensions, allowing for deep penetration into tissue-like organoids and imaging at high temporal and spatial resolution, thereby significantly reducing the need for animal testing and accelerating diagnostic results. It will enable the observation of dynamic processes in real-time and at multiple length scales, facilitating the study of cellular and tissue responses to viral infections or pathogen-induced inflammation. Additionally, it will facilitate high-throughput discovery of novel diagnostic biomarkers.

Overall, this technology represents a major breakthrough in laser technology for high-accuracy and high-throughput medical diagnostics and is poised to make significant contributions to the European laser and biomedical technology landscape.